Once Human

Starry Studio's post-apocalyptic survival game is built around Stardust, a contamination that reaches the soil and the water as well as the living. Polluted food and dirty water cost Sanity, and lost Sanity takes your maximum health down with it, so what you eat is a build decision. Weapons are the other one: roughly a hundred gun blueprints across seven categories, where the perks and accessories bolted on matter more than the gun. A base is placed with a Territory Core and can be relocated whenever you want. The bosses come from another dimension, and beating them is what eases the pollution.